Agustí Lledó

Supramolecular Chemistry and Carbon Nanostructures

Contact info:
Dr. Agusti Lledó
agusti.lledo@udg.edu
Tel. (+34) 972 41 90 80
Website

lledo-team

Selected publications


Agustí Lledó*
Complementary Binding in Urea-Based Self-Folding Cavitands
Org. Lett. 2015, 17, 3770–3773.
DOI: 10.1021/acs.orglett.5b01747

Orion B. Berryman, Aaron C. Sather, Agustí Lledó, Julius Rebek, Jr.
Switchable Catalysis with a Light-Responsive Cavitand
Angew. Chem. Int. Ed. 2011, 50, 9400–9403.
DOI: 10.1002/anie.201105374

Agustí Lledó, Seiji Kamioka, Aaron Sather, Julius Rebek, Jr.
Supramolecular Architecture with a Cavitand – Capsule Chimera
Angew. Chem. Int. Ed. 2011, 50, 1299–1301
Featured in inside cover (February 7th, 2011) and in Chemistry World website, January 24th, 2011.
DOI: 10.1002/anie.201006166

Fernando R. Pinacho Crisóstomo, Agustí Lledó, Siddhartha R. Shenoy, Tetsuo Iwasawa, Julius Rebek, Jr.
Recognition and Organocatalysis with a Synthetic Cavitand Receptor
J. Am. Chem. Soc. 2009, 131, 7402–7410
Featured in the cover (June 3rd, 2009) and in JACS Select issue (J. Am. Chem. Soc. 2009, 131, 17995–17997, December 2009).
DOI: 10.1021/ja900766b

Agustí Lledó, Per Restorp, Julius Rebek, Jr.
Pseudo-Capsule Assemblies Characterized by 19F NMR Techniques
J. Am. Chem. Soc. 2009, 131, 2440–2441.
DOI: 10.1021/ja809224p

+ Publications

Dr. Agustí Lledó

Agustí Lledó (1980, Barcelona) obtained is PhD in Chemistry from the University of Barcelona (UB) in 2006 under the direction of Prof. Antoni Riera. In 2007 he moved to The Scripps Research Institute (TSRI) to pursue post-doctoral studies with Prof. Julius Rebek Jr. In 2010 he returned to his home town and joined the Institute for Research in Biomedicine, Barcelona (IRB Barcelona) as a “Juan de la Cierva” research fellow. In 2014 he moved to University of Girona as a “Ramon y Cajal” (RyC) researcher. His research interests include organic supramolecular chemistry, catalysis an organometallic chemistry. Dr. Lledó leads two ongoing projects at IQCC, one in the area of biomimetic supramolecular catalysis (financed through the RyC program), and another devoted to the bottom up synthesis of carbon nanostructures (financed through “Explora Ciencia” project CTQ2014-61629-EXP). Dr. Lledó also forms part of the DiMoCat group and actively participates of various research projects in the area of transition metal catalyzed reactions.

Research overview

Our research program focuses on two different topics with catalysis as a central leitmotiv. The first research line is directed to the development of biomimetic supramolecular catalysis, i.e., the realization of complex organic transformations catalyzed by artificial receptors mimicking the mode of action of natural enzymes. The second topic seeks to exploit photocatalysis as a new approach towards the bottom up synthesis of carbon nanostructures.

Biomimetic Supramolecular Catalysis

Chemists have long sought to emulate the efficient way in which organic compounds are made in nature, with limited success. One of the distinct features of enzymatic catalysis is the confinement of the substrate in the hydrophobic cavity of the active site. This has multiple consequences for the reaction outcome, including reaction acceleration, modification of the selectivity and suppression of detrimental side reactions thanks to isolation of the substrate from the bulk medium. We seek to emulate this behavior employing cavitands (picture), artificial receptors with a ?-rich hydrophobic pocket and a fluxional behavior akin to those of enzymes. We pursue the preparation of new cavitand receptors with improved binding profiles and functionalities, in order to carry out complex carboacationic cascade reactions in a straightforward manner.

AgustiLledo_RL_1

Carbon Nanostructures

Carbon based nanomaterials promise an exciting technological revolution in the field of materials science, but their mass production still faces important challenges. Single-walled carbon nanotubes (SWNTs), for instance, display distinct and unique electrical properties –which make them desirable for electronic and photovoltaic applications–, but only when obtained uniformly in well-defined dimensions. Graphene and graphene nanoflakes can offer even more astounding properties but bottom up approaches for their preparation are still at its infancy. This research line aims at the preparation of carbon nanostructures using batch processing in solution, exploiting photocatalysis and employing readlily available carbon feedstocks such as olefins or aldehydes.

AgustiLledo_RL_2

People

Principal Investigator

Agustí Lledó

RyC


Staff and Posdocs

Anna Soler

Postdoc


PhD and MACMoM students

Albert Artigas

PhD student (FPI)

Supervisor:
- A. Lledó
- A. Roglans
- M. Solà


Funding

MINECO PROJECTS. Proyectos Explora Ciencia

Project: Processive Synthesis of Well-defined Carbon Nanotubes by Visible Light Photocatalysis of Radical-Cation Diels-Alder Reactions (CaNaDARC)
Researcher: Dr. Agustí Lledó
Reference: CTQ2015-70851-ERC
Funding: 45.000 €
Periode: 2015 – 2017

MINECO PROJECTS. Programa Ramon y Cajal

Project: Programa Ramón y Cajal
Researcher: Dr. Agustí Lledó
Reference: RYC-2012-11112
Funding: 208.600 €
Periode: 2014 – 2019

News

First Science Slam IQCC within Science Week

The Institute of Computational Chemistry and Catalysis of the University of Girona organizes the 1st Science

Review on allenes featured on the cover of Chem. Soc. Rev.

A tutorial review on the use of allenes in transition metal catalyzed cyclodadditions

Second Supramolecular Symposium in Girona

Today took place in Girona the Second Supramolecular Symposium in Girona organized by

Second edition of Science Slam IQCC, November 24, 12.00h

In 2015, the IQCC organized for the first time the Science Slam, which